Nanomanipulation System under Hybrid Microscope combined with ESEM and OM

Micro-Nano manipulation is a key technique for various biological and medical applications. We constructed a unique nanomanipulation system under an environmental- scanning electron microscope (E-SEM) to realize nanoscale manipulation of micro-nano tools for water-containing specimen, especially biological specimen. To observe the inner structure of biological specimen, we combined the optical microscope (OM) with E-SEM including fluorescent observation. As example, we demonstrated a novel method for selective micro-nanoinjection of Caenorhabditis elegans (C. elegans) using nanoprobe tools based on the system. This seminar presents the micro-nano manipulation techniques and their applications with some technical challenges and future directions.
Masahiro Nakajima graduated from Shizuoka University in 2001, and received the Dr. Eng. degree from Nagoya University in 2006. He had been a Research Fellow of MEXT in Micro-Nano Systems Engineering, Nagoya University, from April to May in 2006. He had been a Research Associate of Department of Micro-Nano Systems Engineering, Nagoya University from June 2006 to March 2007. He was an Assistant Professor of Department of Micro-Nano Systems Engineering, Nagoya University from April 2007 to September 2009. From October 2009, he is an Assistant Professor of Center for Micro-nano Mechatronics, Nagoya University. He received Incentive Award of JSME Tokai (2007), Incentive Award of SICE Chubu (2008), two Best Paper Awards in MHS 2009 (2009), two Best Paper Award in MHS 2010 (2010), ICRA 2011 Best Manipulation Paper Award (2011), Best Poster Award in MHS 2011 (2011), and Best Paper Award in MHS 2012 (2012). He has interests in the research fields of the applications of micro/nano-manipulation, nano-assembly, nano-fabrication, nano-devices, nano-mechanics, and nano-biology.